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Assessment of the efficacy of different statins in murine collagen-induced arthritis

✍ Scribed by Gaby Palmer; Véronique Chobaz; Dominique Talabot-Ayer; Sophia Taylor; Alexander So; Cem Gabay; Nathalie Busso


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
146 KB
Volume
50
Category
Article
ISSN
0004-3591

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IL-1 is a key cytokine involved in the inflammatory response. The type II receptor of IL-1 (IL-1RII) acts as a decoy receptor, binding and inhibiting the effect of IL-1. This study was undertaken to establish whether IL-1RII can ameliorate collagen-induced arthritis, a model of inflammatory arthriti