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Effect of hypoxia-inducible factor-1α on transcription of survivin in non-small cell lung cancer

✍ Scribed by Yu-Qing Chen, Cheng-Ling Zhao, Wei Li

Book ID
120698515
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
1021 KB
Volume
28
Category
Article
ISSN
1756-9966

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## Abstract Hypoxia‐inducible factor (HIF)‐1α is the regulatory subunit of HIF‐1 that is stabilized under hypoxic conditions. Under different circumstances, HIF‐1α may promote both tumorigenesis and apoptosis. There is conflicting data on the importance of HIF‐1α as a prognostic factor. This study