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Effect of benzo[a]pyrene on DNA synthesis and DNA polymerase activity of rat liver nuclei

✍ Scribed by Inés Salazar; Laura Tarragó-Litvak; Simón Litvak; Lionel Gil

Book ID
115778630
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
697 KB
Volume
34
Category
Article
ISSN
0006-2952

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Rat liver microsome-mediated binding of
Rat liver microsome-mediated binding of benzo(A)pyrene metabolites to DNA
✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 422 KB 👁 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy