Effect of acidity on the enantiomeric resolution of thyroxine and tocainide by HPLC on a (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid column
✍ Scribed by Hassan Y Aboul-Enein; Imran Ali; Myung Ho Hyun; Yoo Jae Cho; Jong Sun Jin
- Book ID
- 117331280
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 97 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0165-022X
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📜 SIMILAR VOLUMES
## Abstract Flecainide, an antiarrythmic agent, and its analogs were resolved on a high performance liquid chromatographic chiral stationary phase (CSP) based on (+)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid with the use of a mobile phase consisting of methanol‐acetonitrile‐trifluoroacetic acid‐t
## Abstract A chiral stationary phase (CSP **1**) based on (+)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid was applied to the resolution of __N__‐(substituted benzoyl)‐α‐amino acid amides and esters. __N__‐(Substituted benzoyl)‐α‐amino acid amides were well resolved using a mixture of acetic acid‐t