## Abstract Flecainide, an antiarrythmic agent, and its analogs were resolved on a high performance liquid chromatographic chiral stationary phase (CSP) based on (+)โ(18โcrownโ6)โ2,3,11,12โtetracarboxylic acid with the use of a mobile phase consisting of methanolโacetonitrileโtrifluoroacetic acidโt
Spacer length effect of a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid
โ Scribed by Myung Ho Hyun; Do Hun Kim
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 190 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Chiral discrimination observed in high-performance liquid chromatography (HPLC) with the novel chiral stationary phase (CSP-18C6I) derived from (+)-(R)-18-crown-6 tetracarboxylic acid [(+)-18C6H 4 ] was investigated by X-ray crystallographic analysis of the complex composed of the R-enantiomer of 1-
## Abstract Enantiomeric discrimination is observed in the ^1^H and ^13^C NMR spectra of secondary and tertiary amines in the presence of (โ)โ(18โcrownโ6)โ2,3,11,12โtetracarboxylic acid (**1**). Nonequivalence of the resonances of prochiral nuclei in primary and secondary amines is also observed wh