A number of amino acids and derivatives, bought or synthesized, were ลฝ . analyzed by capillary electrophoresis CE with optical active 18-crown-6-tetra-ลฝ . carboxylic acid 18C6H as chiral selector. Besides the primary interaction, i.e., 4 inclusion of the protonated primary amino function in the crow
Chiral Discrimination of Aromatic Amino Acids by Capillary Electrophoresis in (+)- and (-)-(18-Crown-6)-2,3,11,12-tetracarboxylic Acid Selector Modes.
โ Scribed by Wonjae Lee; Sookie La; Youngmie Choi; Kyoung-Rae Kim
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 56 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Enantiomeric discrimination is observed in the ^1^H and ^13^C NMR spectra of secondary and tertiary amines in the presence of (โ)โ(18โcrownโ6)โ2,3,11,12โtetracarboxylic acid (**1**). Nonequivalence of the resonances of prochiral nuclei in primary and secondary amines is also observed wh
## Abstract Flecainide, an antiarrythmic agent, and its analogs were resolved on a high performance liquid chromatographic chiral stationary phase (CSP) based on (+)โ(18โcrownโ6)โ2,3,11,12โtetracarboxylic acid with the use of a mobile phase consisting of methanolโacetonitrileโtrifluoroacetic acidโt