𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Disarming mutant p53 oncogenic function

✍ Scribed by Girardini, Javier E.; Marotta, Carolina; Del Sal, Giannino


Book ID
121368519
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
969 KB
Volume
79
Category
Article
ISSN
1043-6618

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Mutant p53: an oncogenic transcription f
✍ Strano, S; Dell'Orso, S; Di Agostino, S; Fontemaggi, G; Sacchi, A; Blandino, G πŸ“‚ Article πŸ“… 2007 πŸ› Nature Publishing Group 🌐 English βš– 212 KB
Binding of MAR-DNA elements by mutant p5
✍ Wolfgang Deppert πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 952 KB

The tumor suppressor p53 i s a multifunctional protein whose main duty is to preserve the integrety of the genome. This function of wild-type p53 as "guardian of the genome" is achieved at different levels, as a cell cycle checkpoint protein, halting the cell cycle upon DNA damage, and via a direct