𝔖 Bobbio Scriptorium
✦   LIBER   ✦

P53 mutants without a functional tetramerisation domain are not oncogenic

✍ Scribed by Patrick Chène; Elisabeth Bechter


Book ID
115629149
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
263 KB
Volume
286
Category
Article
ISSN
0022-2836

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Mutant p53R270H gain of function phenoty
✍ Christina Heinlein; Frauke Krepulat; Jürgen Löhler; Daniel Speidel; Wolfgang Dep 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 752 KB

## Abstract In human breast cancer, mutations in the __p53__ gene are associated with poor prognosis. However, analysis of patient data so far did not clarify, whether missense point mutations in the __p53__ gene, in addition to causing loss of wild‐type p53 function, also confer a gain of function