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Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?

✍ Scribed by Li, Y; Prives, C


Book ID
110072308
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
135 KB
Volume
26
Category
Article
ISSN
0950-9232

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## Abstract In human breast cancer, mutations in the __p53__ gene are associated with poor prognosis. However, analysis of patient data so far did not clarify, whether missense point mutations in the __p53__ gene, in addition to causing loss of wild‐type p53 function, also confer a gain of function