Direct hybridization of labeled DNA to D
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M. Purrello; I. Balazs
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Article
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1983
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Elsevier Science
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English
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A fast and simple procedure for the hybridization of radioactive probes directly to DNA in agarose gels is described. Restriction endonuclease-digested DNA is fractionated by electrophoresis in agarose gel. After drying, the DNA in the gel is denatured with alkali and annealed with a radioactive pro