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Dipeptidyl Peptidase IV Inhibitors for the Treatment of Diabetes.

โœ Scribed by Ann E. Weber


Publisher
John Wiley and Sons
Year
2004
Weight
10 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract Key step in the improved synthetic pathway to sitagliptin (VII), a new DPPโ€IV inhibitor for the treatment of type 2 diabetes mellitus, is an asymmetric Michael addition to give intermediate (IV).