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Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes

โœ Scribed by H.-J. Mest; R. Mentlein

Publisher
Springer
Year
2005
Tongue
English
Weight
119 KB
Volume
48
Category
Article
ISSN
0012-186X

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## Abstract Key step in the improved synthetic pathway to sitagliptin (VII), a new DPPโ€IV inhibitor for the treatment of type 2 diabetes mellitus, is an asymmetric Michael addition to give intermediate (IV).