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(Dimethylthiocarbamoyl)thio group as a protecting group of phosphates in oligonucleotide synthesis via the phosphotriester approach

โœ Scribed by Takaku, Hiroshi; Kato, Masaatsu; Ishikawa, Shunichi


Book ID
120885807
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
550 KB
Volume
46
Category
Article
ISSN
0022-3263

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4-Cyano-2-butenyl group: A new type of p
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4-Cyano-2-butenyl (CB) is a new type of protecting group for the intemucleotidic bonds in the synthesis of oligodeoxyribonucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild conditions by a 8-elimination pathway using aqueous ammonium h