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Dicationic dithiocarbamate carbapenems with anti-MRSA activity

✍ Scribed by Hideaki Imamura; Norikazu Ohtake; Hideki Jona; Aya Shimizu; Minoru Moriya; Hiroki Sato; Yuichi Sugimoto; Chinatsu Ikeura; Hideo Kiyonaga; Masato Nakano; Rie Nagano; Shinnosuke Abe; Koji Yamada; Terutaka Hashizume; Hajime Morishima

Book ID
108479065
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
208 KB
Volume
9
Category
Article
ISSN
0968-0896

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A series of sulphur-linked and carbon-linked lipophLlic carhapenems has been prepared and evaluated for antibacterial activity in vitro and in vivo and for affinity for PBP2' of Staphylococcus aureus. Potent activity in vitro against methicillin-resistant S. aureus and methicillin-resistant coagulas