Synthesis and antibacterial activity of
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Jean Claude Arnould; Ruth N Illingworth; Wright W Nichols; R. Geoffrey Wilson
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Article
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1996
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Elsevier Science
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English
β 326 KB
A series of sulphur-linked and carbon-linked lipophLlic carhapenems has been prepared and evaluated for antibacterial activity in vitro and in vivo and for affinity for PBP2' of Staphylococcus aureus. Potent activity in vitro against methicillin-resistant S. aureus and methicillin-resistant coagulas