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The synthesis and antibacterial activity of 2-carbolinyl-carbapenems: potent anti-MRSA/MRCNS agents

✍ Scribed by Laura C. Meurer; Ravindra N. Guthikonda; Joann L. Huber; Frank DiNinno


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
362 KB
Volume
5
Category
Article
ISSN
0960-894X

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Synthesis and antibacterial activity of
✍ Jean Claude Arnould; Ruth N Illingworth; Wright W Nichols; R. Geoffrey Wilson πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 326 KB

A series of sulphur-linked and carbon-linked lipophLlic carhapenems has been prepared and evaluated for antibacterial activity in vitro and in vivo and for affinity for PBP2' of Staphylococcus aureus. Potent activity in vitro against methicillin-resistant S. aureus and methicillin-resistant coagulas