𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Detection of MOZ-CBP fusion in acute myeloid leukemia with 8;16 translocation

✍ Scribed by Crowley, J A; Wang, Y; Rapoport, A P; Ning, Y

Book ID
110056492
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
90 KB
Volume
19
Category
Article
ISSN
0887-6924

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Type I MOZ/CBP (MYST3/CREBBP) is the mos
Type I MOZ/CBP (MYST3/CREBBP) is the most common chimeric transcript in acute myeloid leukemia with t(8;16)(p11;p13) translocation
✍ MarΓ­a Rozman; Mireia CamΓ³s; Dolors Colomer; Neus Villamor; Jordi Esteve; Dolors πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 166 KB

## Abstract The t(8;16)(p11;p13) fuses the __MOZ__ (__MYST3__) gene at 8p11 with __CBP__ (__CREBBP__) at 16p13 and is associated with an infrequent but well‐defined type of acute myeloid leukemia (AML) that has unique morphocytochemical findings (monocytoid blast morphology with erythrophagocytosis

A case of inv(8)(p11q24) associated with
A case of inv(8)(p11q24) associated with acute myeloid leukemia involves the MOZ and CBP genes in a masked t(8;16)
✍ Max Chaffanet; Marie-JoΓ«lle Mozziconacci; Francisca Fernandez; Danielle Sainty; πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 365 KB πŸ‘ 3 views

We report on a novel chromosomal aberration, inv(8)(p11q24), in an M5 acute myeloid leukemia. We show by fluorescence in situ hybridization and Southern blot analyses that a t(8;16)(p11;p13) is masked by this inversion. The translocation targets the MOZ gene from the 8p11 and the CBP gene from the 1

Genomic characterization of MOZ/CBP and
Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage-repair mechanism in the origin of the t(8;16)(p11;p13)
✍ Ioannis Panagopoulos; Margareth Isaksson; Charlotta Lindvall; Anna Hagemeijer; F πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 157 KB πŸ‘ 1 views

## Abstract The t(8;16)(p11;p13), which is strongly associated with acute myeloid leukemia (AML) displaying monocytic differentiation, erythrophagocytosis by the leukemic cells, and a poor response to chemotherapy, fuses the __MOZ__ gene (8p11) with the __CBP__ gene (16p13). Although genomic rearra