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Therapy-related acute myeloid leukaemia with t(8;16)(p11;p13);MOZ-CBP and polymorphisms in detoxifying and DNA repair genes

✍ Scribed by Boyd, E M; Bench, A J; Vaghela, K J; Campbell, G N; Chowdhury, F B; Gudgin, E J; Scott, M A; Erber, W N

Book ID
109886758
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
115 KB
Volume
23
Category
Article
ISSN
0887-6924

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## Abstract The t(8;16)(p11;p13) fuses the __MOZ__ (__MYST3__) gene at 8p11 with __CBP__ (__CREBBP__) at 16p13 and is associated with an infrequent but well‐defined type of acute myeloid leukemia (AML) that has unique morphocytochemical findings (monocytoid blast morphology with erythrophagocytosis