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Detection of informative markers for searching a causative gene(s) of cleft lip with palate in A/WySn mice

✍ Scribed by Han, Juan; Shimizu, Takehiko; Shimizu, Kunihiko; Maeda, Takahide


Book ID
123244156
Publisher
Elsevier
Year
2005
Tongue
English
Weight
170 KB
Volume
15
Category
Article
ISSN
0917-2394

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A digenic cause of cleft lip in A-strain
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## Abstract ## BACKGROUND Nonsyndromic cleft lip with or without cleft palate, CL(P), is a common human birth defect with a complex unknown genetic cause. The mouse model is the β€œA/βˆΌβ€ strains. Our previous studies mapped two loci: __clf1__ on Chr11 and __clf2__ on Chr13β€”with a strong genetic mater