Detection of candidate chromosome for cleft lip with palate in A/WySn mice
β Scribed by Yao, Rui; Li, Meng
- Book ID
- 122744156
- Publisher
- Elsevier
- Year
- 2010
- Tongue
- English
- Weight
- 72 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0917-2394
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## Abstract **BACKGROUND:** Genomeβwide association studies are now used routinely to identify genes implicated in complex traits. The panels used for such analyses can detect single nucleotide polymorphisms and copy number variants, both of which may help to identify small deleted regions of the g
## Abstract **BACKGROUND:** Nonsyndromic cleft lip (CL) with or without cleft palate (CLP) is a common human birth defect with complex genetic etiology. One of the unidentified genes maps to chromosome 17q21. A mouse strain, A/WySn, has CLP with complex genetic etiology that models the human defect