Design and Synthesis of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose, a Calcium Ion-Mobilizing Second Messenger
β Scribed by Tsuzuki, Takayoshi; Sakaguchi, Natsumi; Kudoh, Takashi; Takano, Satoshi; Uehara, Masato; Murayama, Takashi; Sakurai, Takashi; Hashii, Minako; Higashida, Haruhiro; Weber, Karin; Guse, Andreas H.; Kameda, Tomoshi; Hirokawa, Takatsugu; Kumaki, Yasuhiro; Potter, Barry V. L.; Fukuda, Hayato; Arisawa, Mitsuhiro; Shuto, Satoshi
- Book ID
- 120498870
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 1009 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0044-8249
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π SIMILAR VOLUMES
4 00 ,6 00 -Didehydro-cADPcR (3), an unsaturated carbocyclic ribose analog of a Ca 2+ -mobilizing second messenger cyclic ADP-ribose (cADPR), was designed and successfully synthesized using a key intramolecular condensation reaction forming the 18-membered pyrophosphate ring structure with a S-pheny