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Synthesis of a New N1-Pentyl Analogue of Cyclic Inosine Diphosphate Ribose (cIDPR) as a Stable Potential Mimic of Cyclic ADP Ribose (cADPR)

✍ Scribed by Aldo Galeone; Luciano Mayol; Giorgia Oliviero; Gennaro Piccialli; Michela Varra


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
110 KB
Volume
2002
Category
Article
ISSN
1434-193X

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ChemInform Abstract: Stereospecific Synt
✍ E. J. HUTCHINSON; B. F. TAYLOR; G. M. BLACKBURN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 41 KB

Stereospecific Synthesis of 1,9-Bis(Ξ²-D-glycosyl)adenines: A Chemical Route to Stable Analogues of Cyclic-ADP Ribose (cADPR). -The title compounds (VIII) and (XI) are prepared for enzyme inhibition studies and for investigation of the agonist/antagonist action at the ryanodine receptor. -(HUTCHINSON