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ChemInform Abstract: Stereospecific Synthesis of 1,9-Bis(β-D-glycosyl)adenines: A Chemical Route to Stable Analogues of Cyclic-ADP Ribose (cADPR).

✍ Scribed by E. J. HUTCHINSON; B. F. TAYLOR; G. M. BLACKBURN


Publisher
John Wiley and Sons
Year
2010
Weight
41 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Stereospecific Synthesis of 1,9-Bis(β-D-glycosyl)adenines: A Chemical Route to Stable Analogues of Cyclic-ADP Ribose (cADPR). -The title compounds (VIII) and (XI) are prepared for enzyme inhibition studies and for investigation of the agonist/antagonist action at the ryanodine receptor. -(HUTCHINSON, E.