## Abstract There is evidence that a putative glioma tumor suppressor locus resides on the long arm of chromosome 19. We present data on 161 gliomas from IS6 patients, which were studied by microsatellite analysis for loss of heterozygosity (LOH) on chromosome 19. Eight loci on the long arm and 2 l
Deletion mapping of interval 6 of the human Y chromosome
✍ Scribed by Maciej Kotecki; Jadwiga Jaruzelska; Malgorzata Skowrońska; Piotr Fichna
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 268 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
DNAs of four individuals demonstrating abnormalities in sexual development and mosaic 45,XO/ 46,XY karyotypes with terminal deletions of Yq were studied using a number of Y-specific probes. The results of these analyses allowed us to map several known DNA fragments within deletion interval 6 in the following order: Ycen -pDP105B/52dA, 50f2E, Fr25-II/Fr15-II, 50f2C, 49f -Yqter (groups of fragments in undetermined order separated by diagonal lines).
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