๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Deletion mapping of 39 random isolated Y-chromosome DNA fragments

โœ Scribed by C. J. J. Oosthuizen; J. S. Herbert; L. K. Vermaak; J. Brusnicky; J. Fricke; L. Plessis; A. E. Retief

Publisher
Springer
Year
1990
Tongue
English
Weight
603 KB
Volume
85
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

โœฆ Synopsis

Thirty-nine recombinants isolated from a Y chromosome-specific library were deletion mapped. Seven deletion intervals were defined by hybridization of probes to DNA of eight individuals with aberrant Y chromosomes. Extreme cytogenetic limits of the deletion intervals were determined by in situ hybridization of one probe per deletion interval. Five intervals, with a total of twenty-five probes, were allocated to the longarm euchromatic region. The probes described will be useful for characterization of aberrant Y chromosomes, in searching for expressed sequences on the Y chromosome, and for further study of the evolutionary relationship between the Y chromosome and other chromosomes.

๐Ÿ“œ SIMILAR VOLUMES

Isolation and characterization of gliobl
Isolation and characterization of glioblastoma-associated homozygously deleted DNA fragments from chromosomal region 9p21 suggests involvement of multiple tumour suppressor genes
โœ Simons, Annet; Jeuken, Judith W. M.; Eleveld, Marc J.; Boerman, Rudolf H.; Geurt ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 269 KB

Representational difference analysis (RDA) of a human glioblastoma xenograft resulted in the isolation of five tumour-associated homozygously deleted DNA fragments, all originating from chromosome 9, region p21. Subsequent analysis of a series of ten glioblastomas using the newly isolated RDA fragme