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Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

✍ Scribed by Orford, Keith W.; Scadden, David T.

Book ID: 109952691
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 918 KB
Volume: 9
Category: Article
ISSN: 1471-0056
DOI: 10.1038/nrg2269

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## Abstract Differentiation and self‐renewal are two primary properties that characterize stem cells. Differentiation of neural stem/precursor cells (NSPCs) gives rise to multiple neural lineages, including neurons, astrocytes, and oligodendrocytes. Self‐renewal, by definition, signifies the progre