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Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells

✍ Scribed by Walkley, Carl R.; Fero, Matthew L.; Chien, Wei-Ming; Purton, Louise E.; McArthur, Grant A.


Book ID
109912399
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
525 KB
Volume
7
Category
Article
ISSN
1465-7392

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## Abstract Differentiation and self‐renewal are two primary properties that characterize stem cells. Differentiation of neural stem/precursor cells (NSPCs) gives rise to multiple neural lineages, including neurons, astrocytes, and oligodendrocytes. Self‐renewal, by definition, signifies the progre