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Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

✍ Scribed by Ito, Keisuke; Hirao, Atsushi; Arai, Fumio; Matsuoka, Sahoko; Takubo, Keiyo; Hamaguchi, Isao; Nomiyama, Kana; Hosokawa, Kentaro; Sakurada, Kazuhiro; Nakagata, Naomi


Book ID
109893327
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
465 KB
Volume
431
Category
Article
ISSN
0028-0836

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Cdk1 is required for the self-renewal of
✍ Wei Wei Zhang; Xiao Jie Zhang; Hui Xian Liu; Jie Chen; Yong Hong Ren; Deng Gao H πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 277 KB

## Abstract Cyclin‐dependent kinase 1 (Cdk1) is indispensible for the early development of the embryo. However, its role in maintaining the undifferentiated state of the embryonic stem (ES) cells remains unknown. In this study, we dissected the function of Cdk1 in mouse ES cells by RNA‐interference