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Dealing with energy demand: the AMP-activated protein kinase

✍ Scribed by Bruce E Kemp; Ken I Mitchelhill; David Stapleton; Belinda J Michell; Zhi-Ping Chen; Lee A Witters


Book ID
114328056
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
105 KB
Volume
24
Category
Article
ISSN
0968-0004

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AMP-activated protein kinase: the energy
✍ D. Grahame Hardie; Simon A. Hawley πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 142 KB

## Abstract The AMP‐activated protein kinase cascade is a sensor of cellular energy charge, and its existence provides strong support for the energy charge hypothesis first proposed by Daniel Atkinson in the 1960s. The system is activated in an ultrasensitive manner by cellular stresses that deplet