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AMP-activated protein kinase: nature's energy sensor

✍ Scribed by Carling, David; Mayer, Faith V; Sanders, Matthew J; Gamblin, Steven J


Book ID
111653402
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
778 KB
Volume
7
Category
Article
ISSN
1552-4450

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AMP-activated protein kinase: the energy
✍ D. Grahame Hardie; Simon A. Hawley πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 142 KB

## Abstract The AMP‐activated protein kinase cascade is a sensor of cellular energy charge, and its existence provides strong support for the energy charge hypothesis first proposed by Daniel Atkinson in the 1960s. The system is activated in an ultrasensitive manner by cellular stresses that deplet