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AMP-activated protein kinase - the key sensor of cellular energy charge

✍ Scribed by D.Grahame Hardie


Book ID
117141503
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
124 KB
Volume
33
Category
Article
ISSN
0022-2828

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AMP-activated protein kinase: the energy
✍ D. Grahame Hardie; Simon A. Hawley πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 142 KB

## Abstract The AMP‐activated protein kinase cascade is a sensor of cellular energy charge, and its existence provides strong support for the energy charge hypothesis first proposed by Daniel Atkinson in the 1960s. The system is activated in an ultrasensitive manner by cellular stresses that deplet