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AMP-activated protein kinase – development of the energy sensor concept

✍ Scribed by D. Grahame Hardie; Simon A. Hawley; John W. Scott

Book ID
110113952
Publisher
Cambridge University Press
Year
2006
Tongue
English
Weight
381 KB
Volume
574
Category
Article
ISSN
0022-3751

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📜 SIMILAR VOLUMES

AMP-activated protein kinase: the energy
AMP-activated protein kinase: the energy charge hypothesis revisited
✍ D. Grahame Hardie; Simon A. Hawley 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

## Abstract The AMP‐activated protein kinase cascade is a sensor of cellular energy charge, and its existence provides strong support for the energy charge hypothesis first proposed by Daniel Atkinson in the 1960s. The system is activated in an ultrasensitive manner by cellular stresses that deplet