Reduction of intracellular pH inhibits c
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Daniela Pirkebner; Michaela Fuetsch; Walter Wittmann; Helmut Weiss; Thomas Halle
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Article
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2003
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John Wiley and Sons
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English
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Cyclooxygenase-2 (COX-2) over-expression is critically involved in tumor formation. Intracellular pH (pHi) has been shown to be alkaline in cancer cells, and to be an important trigger for cell proliferation. This study therefore analyzed the relationship between pHi and COX-2 expression. HRT-18 and