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Cyclooxygenase 2 inhibition regulates differential expression of gamma catenin(Plakoglobin)in human colon cancer

โœ Scribed by Byrne, Sinead; Doherty, Glen; Scully, Geraldine; Prenter, Suzanne; Cox, Claire; Aftab, Ar; Murray, Frank E.; Fitzgerald, Desmond


Book ID
122348537
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
183 KB
Volume
124
Category
Article
ISSN
0016-5085

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Reduction of intracellular pH inhibits c
โœ Daniela Pirkebner; Michaela Fuetsch; Walter Wittmann; Helmut Weiss; Thomas Halle ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 249 KB

Cyclooxygenase-2 (COX-2) over-expression is critically involved in tumor formation. Intracellular pH (pHi) has been shown to be alkaline in cancer cells, and to be an important trigger for cell proliferation. This study therefore analyzed the relationship between pHi and COX-2 expression. HRT-18 and