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Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians

โœ Scribed by Smits, Guillaume; Mungall, Andrew J; Griffiths-Jones, Sam; Smith, Paul; Beury, Delphine; Matthews, Lucy; Rogers, Jane; Pask, Andrew J; Shaw, Geoff; VandeBerg, John L

Book ID
109914210
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
617 KB
Volume
40
Category
Article
ISSN
1061-4036

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Expression of H19 does not influence the
Expression of H19 does not influence the timing of replication of the Igf2/H19 imprinted region
โœ Windham, Colin Q. ;Jones, Peter A. ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 81 KB

Allele specific timing of replication is believed to be a hallmark of imprinted genes, however recent evidence suggests that this might not be the case for the insulin-like growth factor 2 (Igf2) and H19 locus. In this report, we assayed the timing of replication of Igf2 and H19 in two mouse embryon