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Location of enhancers is essential for the imprinting of H19 and Igf2 genes

โœ Scribed by Tilghman, Shirley M.; Webber, Andrea L.; Ingram, Robert S.; Levorse, John M.


Book ID
109780228
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
428 KB
Volume
391
Category
Article
ISSN
0028-0836

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Several human imprinted genes have been identified and are implicated in genetic diseases and tumorigenesis. We studied alterations of two imprinted genes, the paternally imprinted H19 and maternally imprinted IGF2, in 15 ovarian tumors with various cell types. To know allele-specific expression of