𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Conformational studies on the pyridoxal Schiff bases of polypeptides

✍ Scribed by M. Dentini; G. Perretti; M. Savino; P. De Santis; A. S. Verdini

Publisher
Wiley (John Wiley & Sons)
Year
1978
Tongue
English
Weight
520 KB
Volume
17
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

The pyridoxal Schiff bases of the polypeptides poly(L-lysine), poly(L-ornithine), and poly(L-a,y-diaminobutyric acid) were prepared and investigated in water/methanol by CD spectra and equilibrium dialysis experiments. Only the poly(L-a,?-diaminobutyric acid) derivative is characterized by a relevant optical activity similar to that found in pyridoxal enzymes. The stereospecific interactions between the pyridoxylideneimine group and the polypeptide chain prevent the hydrolysis reaction of the aldimine bond.

📜 SIMILAR VOLUMES

Conformational studies on Cu(II) polycom
Conformational studies on Cu(II) polycomplexes of pyridoxal Schiff bases of polypeptides
✍ M. Dentini; M. Savino; P. De Santis; A. S. Verdini 📂 Article 📅 1978 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 490 KB

Structures of Cu(I1) complexes of pyridoxal Schiff bases with poly(L-lysine), poly(L-ornithine), and poly(L-a,?-diaminobutyric acid) were investigated by absorption spectra, CD, and conformational analysis. Although the polypeptides retain their typical right-handed a-helical conformation, opposite

On the Stability of the Schiff Bases of
On the Stability of the Schiff Bases of Pyridoxal 5′-Phosphate with Polypeptides Containing L-Lysine
✍ M. Angeles García del Vado; Gerardo R. Echevarria; Francisco García Blanco; José 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 German ⚖ 506 KB

We determined the apparent equilibrium constant of formation, KpH, of the Schijf bases of pyridoxal 5'-phosphate (PLP) and poly-and copolymers containing L-lysine, as a function of pH at 25" and a constant ionic strength of 0 . 1 ~. The KPH values obtained at acidic and neutral pH were larger that t

Schiff bases of pyridoxal and polyallyla
Schiff bases of pyridoxal and polyallylamine. The formation rate determining step
✍ M. Angeles García Del Vado; Gerardo R. Echevarría Gorostidi; Andrea Basagoitía; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 2 views

The apparent rate constants of formation and hydrolysis of the Schiff bases formed between pyridoxal and polyallylamine has been fitted to a kinetic scheme that involve the different protonated species in the reaction medium and the individual rate constants of formation (k and hydrolysis (k ). The

Determination of the rate of formation o
Determination of the rate of formation of the schiff bases of pyridoxal 5′-phosphate with polyallylamine
✍ M. Angeles Garcí Del Vado; Angel F. Rodríguez Cardona; Gerardo R. Echevarría; Jo 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 586 KB

The formation constants of the Schiff bases of pyridoxal %-phosphate with polyallylamine were determined over the pH range of the acetic-acetate buffer (3.9-5.5) a t an ionic strength of 0.1 M and a temperature of 25°C. The results were consistent with the rapid formation of an ionized carbinolamine

Influence of the side chain on the stabi
Influence of the side chain on the stability of Schiff-bases formed between pyridoxal 5′-phosphate and amino acids
✍ M. A. Vazquez; F. Muñoz; J. Donoso; F. García Blanco 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 527 KB

## Abstract The stability of some Schiff‐bases formed between PLP and different amino acids has been investigated in a wide range of pH. The kinetic constants of formation of these compounds and their hydrolysis rate constants have been determined. Results show that the α‐position of the carboxyl g

Kinetic Study on Stability of Schiff Bas
Kinetic Study on Stability of Schiff Base of Pyridoxal 5′-Phosphate and Leucine in Water Media with Cationic Surfactants
✍ Miguel A. Vázquez; Francisco Muñoz; Josefa Donoso; Francisco García-Blanco 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 German ⚖ 521 KB

We studied the stability of the Schiff bases formed between pyridoxal 5'-phosphate (PLP) and leucine in the presence of (hexadecy1)trimethylammonium bromide (CTAB) over a wide pH range by determining the kinetic constants of formation and hydrolysis of these compounds. The results show that the stab