Kinetic Study on Stability of Schiff Base of Pyridoxal 5′-Phosphate and Leucine in Water Media with Cationic Surfactants
✍ Scribed by Miguel A. Vázquez; Francisco Muñoz; Josefa Donoso; Francisco García-Blanco
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- German
- Weight
- 521 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
We studied the stability of the Schiff bases formed between pyridoxal 5'-phosphate (PLP) and leucine in the presence of (hexadecy1)trimethylammonium bromide (CTAB) over a wide pH range by determining the kinetic constants of formation and hydrolysis of these compounds. The results show that the stability of the Schiffbases is increased by the presence of CTAB as a result of increased rates of formation and decreased hydrolysis rate constants. The ionic head groups of CTAB favour the formation of the bases, while its hydrophobic rests protect the imine double bond from hydrolysis. This model system permits one to obtain partially hydrophobic media with no need for any non-aqueous solvents.