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Computational design of novel cyclic urea as HIV-1 protease inhibitor

โœ Scribed by Vijjulatha, Manga ;Kanth, S.

Book ID
111487992
Publisher
Walter de Gruyter GmbH
Year
2007
Tongue
English
Weight
494 KB
Volume
5
Category
Article
ISSN
2391-5420

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Synthesis of unsymmetric cyclic urea dio
Synthesis of unsymmetric cyclic urea diols, a novel class of HIV protease inhibitors
โœ Benjamin R.P. Stone; Gregory D. Harris; Reginald O. Cann; Thomas E. Smyser; Pat ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 200 KB

Unsymmetric cyclic urea diols of general structure 1 can be prepared either via an isourea derived from the symmetric diamine 2 or by the selective removal of a benzyl group from certain symmetric cyclic ureas 8, employing dissolving metal reduction.