ChemInform Abstract: Unsymmetrical Cyclic Ureas as HIV-1 Protease Inhibitors: Novel Biaryl Indazoles as P2/P2′ Substituents.
✍ Scribed by Mona Patel; James D. Rodgers; Robert J. McHugh Jr.; Barry L. Johnson; Beverly C. Cordova; Ronald M. Klabe; Lee T. Bacheler; Susan Erickson-Viitanen; Soo S. Ko
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
Unsymmetric Nonpeptidic HIV Protease Inhibitors Containing Anthranilamide as a P2' Ligand. -In continuation of an earlier work different kinds of title compounds such as (I) and (II) are synthesized. The structure-activity relationships are discussed. -(RANDAD, RAM-
The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1' Residues. -Among various novel cyclic ureas compounds (VIII) show improved antiviral activity against HIV compared with the lead compounds DMP 323 and DMP 450. -(PATEL,