✦ LIBER ✦

ChemInform Abstract: The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1′ Residues.

✍ Scribed by M. PATEL; L. T. BACHELER; M. M. RAYNER; B. C. CORDOVA; R. M. KLABE; S. ERICKSON-VIITANEN; S. P. SEITZ

Publisher: John Wiley and Sons
Year: 2010
Weight: 37 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199830191

No coin nor oath required. For personal study only.

✦ Synopsis

The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1' Residues. -Among various novel cyclic ureas compounds (VIII) show improved antiviral activity against HIV compared with the lead compounds DMP 323 and DMP 450. -(PATEL,

📜 SIMILAR VOLUMES

ChemInform Abstract: The Synthesis of Sy

ChemInform Abstract: The Synthesis of Symmetrical and Unsymmetrical P1/P1′ Cyclic Ureas as HIV Protease Inhibitors.

✍ M. PATEL; S. P. SEITZ; ET AL. ET AL. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

ChemInform Abstract: Increased Antiviral

ChemInform Abstract: Increased Antiviral Activity of Cyclic Urea HIV Protease Inhibitors by Modifying the P1/P1′ Substituents.

✍ Robert F. Kaltenbach III; Ronald M. Klabe; Beverly C. Cordova; Steven P. Seitz 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Synthesis, Antiviral Activity and Pharma

Synthesis, Antiviral Activity and Pharmacokinetics of P1/P1′ Substituted 3-Aminoindazole Cyclic Urea HIV Protease Inhibitors.

✍ Robert F. III Kaltenbach; et al. et al. 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 22 KB

ChemInform Abstract: Unsymmetrical Cycli

ChemInform Abstract: Unsymmetrical Cyclic Ureas as HIV-1 Protease Inhibitors: Novel Biaryl Indazoles as P2/P2′ Substituents.

✍ Mona Patel; James D. Rodgers; Robert J. McHugh Jr.; Barry L. Johnson; Beverly C. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

ChemInform Abstract: Novel Inhibitors of

ChemInform Abstract: Novel Inhibitors of HIV Protease: Design, Synthesis and Biological Evaluation of Picomolar Inhibitors Containing Cyclic P1/P2 Scaffolds.

✍ Andrew Spaltenstein; Merrick R. Almond; William J. Bock; Darryl G. Cleary; Eric 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Synthesis and Antiviral Activity of P1′

Synthesis and Antiviral Activity of P1′ Arylsulfonamide Azacyclic Urea HIV Protease Inhibitors.

✍ Peggy P. Huang; John T. Randolph; Larry L. Klein; Sudthida Vasavanonda; Tatyana 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 23 KB 👁 1 views