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Synthesis, Antiviral Activity and Pharmacokinetics of P1/P1′ Substituted 3-Aminoindazole Cyclic Urea HIV Protease Inhibitors.

✍ Scribed by Robert F. III Kaltenbach; et al. et al.


Publisher
John Wiley and Sons
Year
2003
Weight
22 KB
Volume
34
Category
Article
ISSN
0931-7597

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The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1' Residues. -Among various novel cyclic ureas compounds (VIII) show improved antiviral activity against HIV compared with the lead compounds DMP 323 and DMP 450. -(PATEL,