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ChemInform Abstract: The Synthesis of Symmetrical and Unsymmetrical P1/P1′ Cyclic Ureas as HIV Protease Inhibitors.

✍ Scribed by M. PATEL; S. P. SEITZ; ET AL. ET AL.

Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1′ Residues.
✍ M. PATEL; L. T. BACHELER; M. M. RAYNER; B. C. CORDOVA; R. M. KLABE; S. ERICKSON- 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1' Residues. -Among various novel cyclic ureas compounds (VIII) show improved antiviral activity against HIV compared with the lead compounds DMP 323 and DMP 450. -(PATEL,