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Comparison of Human and Monkey Peptide Transporters: PEPT1 and PEPT2

โœ Scribed by Zhang, Eric Y.; Emerick, Richard M.; Pak, Youngeen A.; Wrighton, Steven A.; Hillgren, Kathleen M.

Book ID
126004804
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
349 KB
Volume
1
Category
Article
ISSN
1543-8384

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In clinical trials, valganciclovir, the valyl ester of ganciclovir, has been shown to enhance the bioavailability of ganciclovir when taken orally by patients with cytomegalovirus infection. We investigated the role of the intestinal peptide transporter PEPT1 in this process by comparing the interac