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Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2

โœ Scribed by Malliga E Ganapathy; Puttur D Prasad; Bryan Mackenzie; Vadivel Ganapathy; Frederick H Leibach


Book ID
117048592
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
283 KB
Volume
1324
Category
Article
ISSN
0005-2736

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Transport of valganciclovir, a ganciclov
โœ Mitsuru Sugawara; Wei Huang; You-Jun Fei; Frederick H. Leibach; Vadivel Ganapath ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 231 KB

In clinical trials, valganciclovir, the valyl ester of ganciclovir, has been shown to enhance the bioavailability of ganciclovir when taken orally by patients with cytomegalovirus infection. We investigated the role of the intestinal peptide transporter PEPT1 in this process by comparing the interac