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Communicating and Understanding the Purpose of Pediatric Phase I Cancer Trials

✍ Scribed by Cousino, M. K.; Zyzanski, S. J.; Yamokoski, A. D.; Hazen, R. A.; Baker, J. N.; Noll, R. B.; Rheingold, S. R.; Geyer, J. R.; Alexander, S. C.; Drotar, D.; Kodish, E. D.


Book ID
121354473
Publisher
American Society of Clinical Oncology
Year
2012
Tongue
English
Weight
199 KB
Volume
30
Category
Article
ISSN
0732-183X

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Phase I Clinical Trials in children with cancer are carried out with therapeutic intent, so as to define antileukemic/antitumor activity, dose-limiting toxicity, maximum tolerated dosage, and pharmacokinetics. These studies define a dosage of an agent or combination that may be used in a larger stud