## Abstract Trimetrexate (TMTX), a lipophilic antifol, was evaluated in a Pediatric Oncology Group (POG) Phase I trial in children with refractory solid tumors. TMTX was administered intravenously daily ร 5 every three weeks. Starting dose was 6.4 mg/m^2^/day. Dose was escalated by 20% until the ma
The importance of Phase I/II trials in pediatric oncology
โ Scribed by Craig A. MacArthur; Teresa Vietti
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 285 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0167-6997
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