𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease

✍ Scribed by Vootele Võikar; Heikki Rauvala; Elina Ikonen

Book ID
117345138
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
389 KB
Volume
132
Category
Article
ISSN
0166-4328

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Decreased purinergic inhibition of synap
Decreased purinergic inhibition of synaptic activity in a mouse model of Niemann-Pick disease type C
✍ Su-ya Zhou; Shu-jun Xu; Ying-gang Yan; Hui-mei Yu; Shu-cai Ling; Jian-hong Luo 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 715 KB

## Abstract Niemann‐Pick disease type C (NPC) is a progressive neurodegenerative disorder characterized by accumulation of free cholesterol in lysosomes, mainly due to a mutation in the NPC1 gene. The pathophysiological basis of the neural disorders in NPC, however, is not well understood. We found