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Clinical impact of nucleophosmin mutations and Flt3 internal tandem duplications in patients older than 60 yr with acute myeloid leukaemia

✍ Scribed by Sebastian Scholl; Claudia Theuer; Veit Scheble; Christa Kunert; Anita Heller; Lars-Olof Mügge; Hans-Joerg Fricke; Klaus Höffken; Ulrich Wedding


Book ID
114794349
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
120 KB
Volume
80
Category
Article
ISSN
0902-4441

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## Abstract Partial tandem duplication (PTD) of the __MLL__ gene and internal tandem duplication (ITD) of the juxtamembrane region of the __FLT3__ receptor tyrosine kinase gene have been described in acute myeloid leukemia (AML) patients, preferentially in those with normal cytogenetics. These alte