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Clinical impact of internal tandem duplications and activating point mutations in FLT3 in acute myeloid leukemia in elderly patients

✍ Scribed by Anna Andersson; Bertil Johansson; Carin Lassen; Felix Mitelman; Rolf Billström; Thoas Fioretos


Book ID
114792630
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
144 KB
Volume
72
Category
Article
ISSN
0902-4441

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## Abstract Partial tandem duplication (PTD) of the __MLL__ gene and internal tandem duplication (ITD) of the juxtamembrane region of the __FLT3__ receptor tyrosine kinase gene have been described in acute myeloid leukemia (AML) patients, preferentially in those with normal cytogenetics. These alte

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