cis-1-Amino-1,2,3,4-tetrahydro-2-naphthalenol: Resolution and Application to the Catalytic Enantioselective Reduction of Ketones. -The optically active title amino alcohols are prepared by optical resolution of racemic amino alcohols with (-)-mandelic acid and used in the asymmetric reduction of ke
cis-2-Amino-1-acenaphthenol: Practical resolution and application to the catalytic enantioselective reduction of ketones
โ Scribed by Atsushi Sudo; Masaru Matsumoto; Yukihiko Hashimoto; Kazuhiko Saigo
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 200 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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๐ SIMILAR VOLUMES
The cbiral amino alcohol, cis-Zamino-1-acenaphthenol, was synthesized, and resolved by a simple procedure. This new chiral amino alcohol was converted into an oxaxoline derivative and applied as a chiral auxiliary to the diastereoselective (2.3]-Wittig rearrangement.
The amino alcohol rac-1-(1,2,3,4-tetrahydroisoquinoline-1-yl)-cyclopentanol was resolved via its O,O'-dibenzoyl-tartaric acid salt. These enantiomeric amino alcohols were used in the enantioselective reduction of prochiral aryl alkyl ketones. The resulting secondary alcohols were obtained in high en
## A new class of oxozoboroltdine cotaIysts has been preporedjwn opticoliy pure cis-l-amino-2-indonols whtch ore ovoilable in loge quantities. The o~wnetric borone reduction of aromatic ketones using these catalysts has been studied.