ChemInform Abstract: cis-1-Amino-1,2,3,4-tetrahydro-2-naphthalenol: Resolution and Application to the Catalytic Enantioselective Reduction of Ketones.

✍ Scribed by S. HIGASHIJIMA; H. ITOH; Y. SENDA; S. NAKANO

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 28 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199806045

✦ Synopsis

cis-1-Amino-1,2,3,4-tetrahydro-2-naphthalenol: Resolution and Application to the Catalytic Enantioselective Reduction of Ketones.

-The optically active title amino alcohols are prepared by optical resolution of racemic amino alcohols with (-)-mandelic acid and used in the asymmetric reduction of ketones such as (I) or (III). An increase in selectivity is observed with increasing temperature. -(HIGASHIJIMA, S.; ITOH, H.; SENDA, Y.;